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Takeda and Iambic Sign Multi-Year Drug Discovery Collaboration

At a glance

  • Takeda and Iambic Therapeutics entered a multi-year agreement
  • The partnership focuses on oncology and gastrointestinal drug programs
  • Iambic may receive over $1.7 billion plus royalties

Takeda Pharmaceuticals and Iambic Therapeutics announced a multi-year technology and discovery collaboration on February 9, 2026, focusing on drug development in specific therapeutic areas.

The agreement centers on advancing small molecule programs for oncology, as well as gastrointestinal and inflammation treatments. According to Iambic Therapeutics, Takeda will gain access to specialized technology for predicting protein-ligand complexes.

Under the terms of the collaboration, Takeda will utilize Iambic’s NeuralPLexer model as part of the drug discovery process. The partnership aims to apply this technology to support research in the targeted therapeutic fields.

Iambic is eligible to receive a range of payments as part of the agreement. These include upfront fees, research cost coverage, and technology access payments, in addition to success-based payments and royalties on future product sales.

What the numbers show

  • The agreement was announced on February 9, 2026
  • Iambic could receive payments exceeding $1.7 billion
  • Royalties on net sales are included in the compensation structure

The collaboration was publicly reported by both Iambic Therapeutics and Life Sciences Times on the day of the announcement. The partnership is structured to provide financial incentives based on research and commercial milestones.

The initial phase of the agreement will focus on small molecule programs in Takeda’s oncology and gastrointestinal and inflammation therapeutic areas. The use of Iambic’s NeuralPLexer model is expected to support these research efforts.

Both companies have described the agreement as a multi-year commitment to advancing drug discovery in the specified therapeutic areas. The arrangement includes provisions for ongoing technology access and potential future payments tied to the success of resulting products.

* This article is based on publicly available information at the time of writing.

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